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Pipeline
  OT–551:
Dry AMD
  OT–730:
Glaucoma
  OT–304 Program:
Cancer and
Inflammatory
Diseases

pipeline

Othera currently has three product development programs in process. Our most advanced clinical-stage product, OT-551, is a proprietary small molecule, delivered topically by eye drop, under development for Geographic Atrophy, the severe dry form of age-related macular degeneration (AMD). In addition, we are currently in pre-clinical development for a second eye drop, OT-730, for the treatment of glaucoma. Othera is also developing OT-304, an oral small molecule for the treatment of cancer and cancer-associated thrombosis. In support of this program, Othera is continuing to discover analogs of OT-304 to build a diverse library of backup compounds and potential new leads to treat various non-ophthalmic diseases, including cancer and inflammatory diseases.

  Lead Opt. Preclinical Phase 1 Phase 2 Phase 3
ophthalmology
OT-551 (topical)
Geographic Atrophy (Dry AMD)
OT-730 (topical)
Glaucoma
oncology
OT-304 (oral)
Anti-Tumor Therapy
Thrombosis (Cancer-Associated)
inflammatory diseases
OT-300 Series (oral)